RBR-3jv46h Effects of beta-alanine supplementation in muscle strength and mass.

Date of registration: 06/19/2020 ^(mm/dd/yyyy)
Last approval date : 06/19/2020 ^(mm/dd/yyyy)

Study type:

Interventional

Scientific title:

Trial identification

• UTN code: U1111-1247-9340

• Public title:

  en

  Effects of beta-alanine supplementation in muscle strength and mass.

  pt-br

  Efeitos da suplementação de beta alanina na força e massa muscular.

• Scientific acronym:

• Public acronym:
• Secondaries identifiers:
  • 65969917.4.0000.5507
    Issuing authority: Plataforma Brasil
  • 2.094.534
    Issuing authority: Comitê de Ética em Pesquisa da Universidade Metodista de Piracicaba

Sponsors

• Primary sponsor: Universidade Metodista de Piracicaba
• Secondary sponsor:
  • Institution: Universidade Metodista de Piracicaba
• Supporting source:
  • Institution: Universidade Metodista de Piracicaba

Health conditions

• Health conditions:

  en

  Sports Nutritional Physiological Phenomena

  pt-br

  Fenômenos Fisiológicos da Nutrição Esportiva

• General descriptors for health conditions:

  en

  C23 Pathological conditions, signs and symptoms

  pt-br

  C23 Condições patológicas, sinais e sintomas

  es

  C23 Condiciones patológicas, signos y síntomas

• Specific descriptors:

Interventions

• Interventions:

  en

  The aim of the present study will be to assess neuromuscular adaptations (maximal strength and muscle hypertrophy) induced by an 8-week period of beta alanine supplementation. 20 resistance-trained men (18-35 years) will participate in this double-blind placebo controled trial, being allocated in one of the following groups: BA (6.4g/day of beta-alanine); PL (6.4g/day of maltodextrin). Subjects will be instructed to consume the supplement concomitant with meals. Maximal strength, muscular endurance and muscle thickness will be assessed in the pre and post intervention periods.

  pt-br

  O objetivo do presente estudo será analisar as adaptações neuromusculares (força máxima e hipertrofia muscular) decorrentes da suplementação de beta-alanina por oito semanas. 20 indivíduos (18-35 anos; experiência com treinamento de força mínima de um ano) participarão deste ensaio clínico randomizado duplo-cego, sendo alocados em um dos seguintes grupos: BA (6,4g/dia de beta-alanina); PL (6,4g/dia de maltodextrina). Os sujeitos serão instruídos a ingerirem o suplemento juntamente às refeições. Serão analisados, pré e pós intervenção, os seguintes parâmetros: força máxima de membros superiores e inferiores, resistência de força, espessura muscular.

• Descriptors:

  en

  G07.203.300.456 Dietary Supplements

  pt-br

  G07.203.300.456 Suplementos Nutricionais

  es

  G07.203.300.456 Suplementos Dietéticos

Recruitment

• Study status: Data analysis completed
• Countries
  • Brazil
• Date first enrollment: 03/01/2018 ^(mm/dd/yyyy)

• Target sample size:	Gender:	Minimum age:	Maximum age:
  20	M	18 Y	35 Y

• Inclusion criteria:

  en

  individuals should have a minimum experience of 6 months with the regular practice of strength training; training frequency greater than or equal to three weekly sessions.

  pt-br

  Os indivíduos deveriam apresentar a experiência mínima de 6 meses com a pratica regular do treinamento de força; frequência de treino superior ou igual a três sessões semanais.

• Exclusion criteria:

  en

  Those who might have clinical limitations that could compromise their health and safety would be excluded. Those who practice other types of strength training would also be excluded. During the period, the volunteer who was injured, regardless of the reason, or if he was absent from more than three consecutive training sessions, would be excluded from the sample.

  pt-br

  Seriam excluídos aqueles que porventura apresentassem limitações clinicas que pudessem comprometer a saúde e segurança dos mesmos. Seriam excluídos também aqueles que praticassem outras modalidades de treinamento de força. Durante o período, o voluntario que se lesionasse, independente do motivo, ou se ausentasse de mais de três treinos consecutivos, seria excluído da amostra.

Study type

• Study design:

• Expanded access program	Purpose	Intervention assignment	Number of arms	Masking type	Allocation	Study phase
  	Treatment	Parallel	2	Double-blind	Randomized-controlled	N/A

Outcomes

• Primary outcomes:

  en

  Expected outcome:Significant increases in lower limb muscle thickness were expected to be induced by beta alanine supplementation, as measured by ultrasound.

  pt-br

  Desfecho esperado: Esperava-se aumentos significantes na espessura muscular de membros inferiores induzidos pela suplementação de beta alanina, mensurada pela ultrassonografia.

  en

  Observed outcome:No significant differences were observed with supplementation (Beta Alanine: 5.9%; Placebo: 9.3%)

  pt-br

  Desfecho encontrado:Não foram observadas diferenças significantes com a suplementação (Beta alanina: 5,9%; Placebo: 9,3%)

• Secondary outcomes:

  en

  Expected outcome: It was expected significant increases in muscle strength of lower and upper limbs induced by beta alanine supplementation, assessed through 1RM test.

  pt-br

  Desfecho esperado: Esperava-se aumentos significantes na força musuclar de membros inferiores induzidos pela suplementação de beta alanina, mensurada pelo teste de 1RM.

  en

  Observed outcome:No differences were observed induced by supplementation (Beta alanine: 17,1%; Placebo: 17,5%)

  pt-br

  Desfecho encontrado:Não foram observadas diferenças significantes com a suplementação (Beta alanina: 17,1%; Placebo: 17,5%)

Contacts

• Public contact
  • Full name: Julio Benvenutti Bueno de Camargo
  • • Address: Rua dos Cravos
    • City: piracicaba / Brazil
    • Zip code: 13405-077
  • Phone: +55-19-991180143
  • Email: julio.bbc@gmail.com
  • Affiliation: Universidade Metodista de Piracicaba
   
• Scientific contact
  • Full name: Julio Benvenutti Bueno de Camargo
  • • Address: Rua dos Cravos
    • City: piracicaba / Brazil
    • Zip code: 13405-077
  • Phone: +55-19-991180143
  • Email: julio.bbc@gmail.com
  • Affiliation: Universidade Metodista de Piracicaba
   
• Site contact
  • Full name: Julio Benvenutti Bueno de Camargo
  • • Address: Rua dos Cravos
    • City: piracicaba / Brazil
    • Zip code: 13405-077
  • Phone: +55-19-991180143
  • Email: julio.bbc@gmail.com
  • Affiliation: Universidade Metodista de Piracicaba
   

Additional links:

• Download in ICTRP format